Can Obesity Kill you? How Does Orlistat Work?

 

Morbid or class III obesity, that of a body mass index (BMI) greater than 40 kg / m2, is linked to higher death rates, according to a study published in "PLoS Medicine." Carl Kitahara and her colleagues at the National Cancer Institute (USA) found that death rates from a wide range of diseases, especially heart disease, cancer and diabetes, were higher in morbidly obese individuals. compared to those in the normal weight range.

The researchers reached these conclusions by pooling data from 20 prospective cohort studies, primarily from the US, from the US National Cancer Institute Cohort Consortium. After excluding people who had always smoked and those with a history of chronic disease, the analysis included 9,564 adults who were classified as class III obese based on their height and weight at baseline and 304,011 adults of normal weight.

Among participants with class III obesity, death rates (deaths per 100,000 people per year) during the 30-year study period were 856 and 663 for men and women, respectively, compared to death rates for men and women of normal weight, who were 346.7 and 280.5, respectively. You can Buy Weight Loss Pills like Orlistat Online in the UK, Orlistat is in a class of medications called lipase inhibitors. It works by preventing some of the fats in the food consumed from being absorbed in the intestines. These fats that were not absorbed are then eliminated from the body in the stool thanks to the effect of these weight loss pills.

Heart, cancer and diabetes
Heart disease is the main cause of the highest death rate among obese class III individuals, followed by cancer and diabetes. On the other hand, the risk of death from any cause and death from heart disease, cancer, diabetes, and other pathologies increases with increasing BMI. Compared with those of normal weight, a BMI between 40 and 59 kg / m2 translates into an estimated loss of 6.5 to 13.7 years of life.

However, the investigators acknowledge that the precision of these results is limited by the majority use of measurements of height and weight provided by participants to calculate BMI and by the use of BMI as the sole measure of obesity. These results may not be extrapolated to all populations, but indicate that morbid obesity is associated with a substantial increase in the mortality rate and highlight the need to develop more effective interventions to reduce this type of obesity.

Deadly like tobacco
The authors conclude that “Class III obesity is associated with excess total mortality rates and mortality due to a wide range of causes, particularly heart disease, cancer and diabetes, and the risk of death in general and for these specific causes it continues to increase as BMI values ​​rise ».

And they add: "We have detected that the reduction in life expectancy associated with morbid obesity is similar for BMI values ​​above 50 kg / m2, even greater than that observed for current smokers", the researchers conclude.